Old-Fashioned Ground Beef & Biscuit Casserole

This classic casserole is a cozy, family-friendly dish that layers savory ground beef, creamy mushroom sauce, colorful vegetables, and golden biscuits on top. It’s the ultimate comfort food for busy weeknights — hearty, satisfying, and ready in under an hour!

Ingredients

• 1 lb ground beef (80/20 for flavor or 90/10 for leaner option)

• 1 medium onion, chopped

• 2 cloves garlic, minced

• 1 can (10.75 oz) condensed cream of mushroom soup

• 1 cup frozen mixed vegetables (peas, carrots, corn, green beans)

• 1 cup shredded cheddar cheese

• 1 can (16.3 oz) refrigerated biscuits

• Salt & pepper, to taste

Instructions

1. Preheat oven to 375°F (190°C). Grease a 9×13-inch baking dish.

2. Cook beef mixture: In a large skillet, cook ground beef, onion, and garlic over medium heat until beef is browned. Drain excess fat.

3. Add sauce & veggies: Stir in cream of mushroom soup, frozen vegetables, salt, and pepper. Simmer for 5 minutes until heated through.

4. Assemble casserole: Pour beef mixture into the prepared baking dish and spread evenly. Sprinkle cheddar cheese on top.

5. Add biscuits: Arrange refrigerated biscuits over the beef mixture in a single layer.

6. Bake: Place in the oven and bake for 20-25 minutes or until biscuits are golden brown and cooked through.

7. Serve: Let rest 5 minutes before serving.

Serving Suggestions

• Serve with a crisp garden salad or steamed broccoli to balance the richness.

• Pair with mashed potatoes or buttery corn on the cob for a heartier meal.

• Top with a sprinkle of fresh parsley or green onions before serving.

• Serve with ketchup or brown gravy for dipping.

Recipe Variations

• Tex-Mex Style: Use cream of cheddar soup, add taco seasoning, and top with pepper jack cheese.

• Italian Twist: Swap mushroom soup for marinara sauce and use mozzarella cheese.

• Breakfast Bake: Use cooked breakfast sausage instead of beef and top with scrambled eggs.

• BBQ Casserole: Stir in ½ cup barbecue sauce with the beef mixture for a smoky flavor.

• Low-Carb Option: Replace biscuits with cauliflower florets or skip them entirely.

• Homemade Touch: Use from-scratch mushroom gravy and homemade drop biscuits.

20 Expert Tips for the Best Biscuit Casserole

1. Use lean beef if you want a lighter dish, but season generously for flavor.

2. Drain the beef well — excess grease can make the casserole soggy.

3. Cook frozen vegetables just until heated to keep them from turning mushy.

4. For extra flavor, add a splash of Worcestershire sauce to the beef mixture.

5. Use sharp cheddar for a stronger cheese flavor.

6. Arrange biscuits evenly so they cook through and brown nicely.

7. Brush biscuits with melted butter before baking for a golden, glossy finish.

8. If biscuits brown too quickly, cover with foil for the last 10 minutes of baking.

9. Pre-bake biscuits separately if you like them extra crisp, then place on top before serving.

10. Add sautéed mushrooms for extra earthy flavor.

11. If using fresh vegetables, blanch them first so they cook evenly.

12. Season each layer — beef, sauce, and topping — for the most flavorful casserole.

13. Let the casserole rest for 5-10 minutes before cutting to allow filling to set.

14. Make-ahead friendly: assemble the beef mixture a day early, refrigerate, then add biscuits before baking.

15. To make it creamier, stir in ¼ cup sour cream or cream cheese before baking.

16. Add a layer of mashed potatoes under the biscuits for a “shepherd’s pie” vibe.

17. Double the recipe for potlucks — this dish is a crowd-pleaser!

18. Store leftovers in an airtight container and reheat in the oven for best texture.

19. Use a cast-iron skillet to cook and bake in one dish for easy cleanup.

20. Experiment with different biscuit flavors — cheddar, garlic, or honey butter.

20 Most Asked Questions (FAQs)

1. Can I use fresh vegetables instead of frozen?
Yes! Just blanch them briefly to soften before adding to the mixture.

2. Can I use a different soup?
Absolutely — cream of chicken, cream of celery, or cream of cheddar all work well.

3. Can I make this ahead of time?
Yes, assemble the beef mixture, refrigerate, then top with biscuits right before baking.

4. Can I freeze this casserole?
Yes, freeze before adding biscuits. When ready, thaw, top with fresh biscuits, and bake.

5. Can I use homemade biscuits?
Yes, just adjust bake time slightly if biscuits are thicker.

6. Can I use ground turkey or chicken?
Yes, just season well for flavor — poultry can be milder.

7. How do I make it vegetarian?
Use plant-based crumbles and cream of mushroom soup.

8. Can I add more vegetables?
Yes! Corn, peas, bell peppers, spinach, and green beans all work well.

9. Can I make it gluten-free?
Yes, use gluten-free soup and gluten-free biscuits.

10. How do I keep biscuits from being doughy?
Bake until golden brown, and make sure filling is hot before adding biscuits.

11. Can I use shredded hash browns in the filling?
Yes, add about 1 cup to make it heartier.

12. Can I add cheese under the biscuits?
Definitely! A layer of cheese under biscuits makes them extra cheesy.

13. Can I make it spicy?
Add chili powder, red pepper flakes, or diced jalapeños to the beef mixture.

14. Can I bake this in a smaller dish?
Yes, but the filling will be thicker — you may need extra bake time.

15. Can I use leftover biscuits?
Yes, just crumble them on top and bake until hot and golden.

16. Can I add gravy instead of soup?
Yes, brown or mushroom gravy makes a rich alternative.

17. Can I double the cheese?
Absolutely — extra cheese makes it even more comforting.

18. Can I make it dairy-free?
Yes, use dairy-free cheese and a dairy-free cream soup substitute.

19. How long does it keep in the fridge?
Up to 3 days in an airtight container.

20. How do I reheat leftovers?
Reheat in the oven at 350°F until warm for best texture.